However, several epidemiologic studies on clinical presentation of AA have reported that onset before adolescence is one of the important prognostic factors ( 4).
#Alopecia universalis treatment 2011 full#
AT and AU are severe forms of AA and only 10% of patients with AT/AU experience full recovery ( 2, 3).ĪA is characterized by a variety of clinical courses, and it is not easy for clinicians to predict prognosis and clinical outcome of each patient. The hair of the entire scalp and the whole body can be affected, which are called alopecia totalis (AT) and alopecia universalis (AU), respectively. Although it usually presents as asymptomatic localized hair loss (patch AA), it is a disease of very broad spectrum. It is suggested that patients with AU or family history of AA make worse progress in the early-onset group than in the late-onset group.Īlopecia areata (AA) is a common disorder that accounts for 1%-3% of patients visiting dermatology clinics ( 1).
Systemic evaluations might be needed in early-onset patients due to the higher incidence of comorbid diseases. In the early-onset group, patients with AU or a family history of AA showed worse prognosis, whereas this trend was not observed in the late-onset group. All treatment modalities failed to show any association with the present hair condition of patients. In addition, significantly more patients with concomitant medical disorders, especially allergic diseases were found in the early-onset group (45.8%) than in the late-onset group (31.2%). These clinical differences were more prominent in patients with AU than in those with AT. We found that more patients in the early-onset group had a family history of AA, nail dystrophy, and history of atopic dermatitis than those in the late-onset group. Based on the onset age around adolescence (< or ≥ 13 yr), 108 patients were classified in an early-onset group and the other 179 patients in a late-onset group.
In this study, we investigated the clinical characteristics of AT/AU according to the onset age.
#Alopecia universalis treatment 2011 Patch#
Alopecia totalis (AT) and alopecia universalis (AU), severe forms of alopecia areata (AA), show distinguishable clinical characteristics from those of patch AA.
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